The Role Of Force Generation By Target Cells In HIV‐1 Entry And Fusion
Human immunodeficiency virus (HIV) is a causative agent of AIDS, which is a major cause of mortality in all age categories, including children.…
RNASeq for Clinical Diagnosis of Neuromuscular Diseases
The primary objective of this proposal is to evaluate whether targeted RNASeq has the potential to assist in the clinical diagnosis of the causes…
Programmed Immune Response and Avoidance with Virus-Like Nanoparticles, and Click Chemistry Solutions to Line Infections
This is half of an effort originally funded under the title “Programmed Immune Response and Avoidance with Virus-Like Nanoparticles.” We pivoted…
mRNA-based Therapeutics for the Treatment of hRSV Infections
Why a new treatment for hRSV? Human respiratory syncytial virus (hRSV) is the leading cause of viral pneumonia,…
Identification of Peptide-based Activators and Inhibitors of the CFTR Protein, for Research or Therapeutic Use
This technology targets two roles of the CFTR protein: one related to the lethal genetic disease, Cystic Fibrosis (CF), and one related to…
Hemodynamics of Neutrophil Trafficking in the CF Pulmonary Vasculature
Massive neutrophil infiltration into the airways is a hallmark of the chronic inflammatory response in cystic fibrosis (CF) and occurs even in the…